Signed conjunctive normal form (signed CNF) is a classical conjunctive clause form using a generalized notion of literal, called signed atom. A signed atom is an expression of the form Ë Ô, where Ô is a classical atom and Ë, its sign, is a subset of a domain Æ . The informal meaning is “Ô takes one of the values in Ë”. Applications for deduction in signed logics derive from those of annotated logic programming (e.g., mediated deductive databases), constraint programming (e.g., scheduling), and many-valued logics (e.g., natural language processing). The central rˆole of signed CNF justifies a detailed study of its subclasses, including algorithms for and complexities of associated SAT problems. Continuing our previous work [1], in this paper we present new results on the complexity of the signed 2-SAT problem; i.e., the case in which all clauses of a signed CNF formula have at most two literals.