Groupware systems allow remote collaboration via computer in a simple, economic and efficient way. However, to be universally valuable, groupware systems must be accessible and usable for all, including the differently-abled. In this paper we discuss the results of testing the accessibility and usability of Google Docs (http://docs.google.com) when using a screen reader and a voice synthesizer, and suggest some basic guidelines for designing effective, efficient and satisfactory User Interfaces (UIs).