Adaptive SPECT

Abstract--Adaptive imaging systems alter their dataacquisition configuration or protocol in response to the image information received. An adaptive pinhole SPECT system might acquire an initial scout image to obtain preliminary information about the radiotracer distribution and then adjust the configuration or sizes of the pinholes, the magnifications or the projection angles in order to improve performance. This paper briefly describes two small-animal SPECT systems that allow this flexibility and then presents a framework for evaluating adaptive systems in general, and adaptive SPECT systems in particular. The evaluation is in terms of the performance of linear observers on detection or estimation tasks. Expressions are derived for the ideal linear (Hotelling) observer and the ideal linear (Wiener) estimator with adaptive imaging. Detailed expressions for the performance figures of merit are given, and possible adaptation rules are discussed.

• Type: Journal
• Year: 2008
• Where: TMI
• Authors: Harrison H. Barrett, L. R. Furenlid, M. Freed, J. Y. Hesterman, Matthew A. Kupinski, Eric Clarkson, M. K. Whitaker
• Keywords: Adaptive, Adaptive Imaging, Adaptive Pinhole Spect, TMI 2008