Agent-Based Model of Genotype Editing

Evolutionary algorithms rarely deal with ontogenetic, non-inherited alteration of genetic information because they are based on a direct genotype-phenotype mapping. In contrast, in Nature several processes have been discovered which alter genetic information encoded in DNA before it is translated into amino-acid chains. Ontogenetically altered genetic information is not inherited but extensively used in regulation and development of phenotypes, giving organisms the ability to, in a sense, re-program their genotypes according to environmental cues. An example of post-transcriptional alteration of gene-encoding sequences is the process of RNA Editing. Here we introduce a novel Agent-based model of genotype editing and a computational study of its evolutionary performance in static and dynamic environments. This model builds on our previous Genetic Algorithm with Editing, but presents a fundamentally novel architecture in which coding and non-coding genetic components are allowed to co-e...

• Type: Journal
• Year: 2007
• Where: EC
• Authors: Chien-Feng Huang, Jasleen Kaur, Ana Gabriela Maguitman, Luis Mateus Rocha
• Keywords: EC 2007, ECommerce, Evolutionary, Genetic Information, Genotype