: Changing business requirements such as providing new business services lead to an ongoing need for fast and flexible adaptation of the underlying information systems and infrastructure. Thus integration is a recurring task to realize complex ebusiness processes. This paper outlines a concept for a model-driven framework for process based integration in the area of e-business. At first the results of domain engineering within three different companies are presented and used as a starting point to develop the framework concept with high-level domain-specific integration pattern as core. This concept will lead to the closure of the gap between business requirements and technical implementations and help raising the reuse of solution knowledge of system integrators.