ional models of cortical associative memory often take a top-down approach. We have previously described such an abstract model with a hypercolumnar structure. Here we explore a similar, biophysically detailed but subsampled network model of neocortex. how the neurodynamics and associative memory properties of this biophysical model relate to the abstract model as well as to experimental data. The resulting network exhibits attractor dynamics; pattern completion and pattern rivalry. It reproduces several features of experimentally observed local UP states, as well as oscillatory behavior on the gamma and theta time scales observed in the cerebral cortex. r 2006 Elsevier B.V. All rights reserved.