Automatic Reading System for On-off Type DNA Chip

: In this study we propose an automatic reading system for diagnostic DNA chips. We define a general specification for an automatic reading system and propose a possible implementation method. The proposed system performs the whole reading process automatically without any user intervention, covering image acquisition, image analysis, and report generation. We applied the system for the automatic report generation of a commercialized DNA chip for cervical cancer detection. The fluorescence image of the hybridization result was acquired with a GenePixTM scanner using its library running in HTML pages. The processing of the acquired image and the report generation were executed by a component object module programmed with Microsoft Visual C++ 6.0. To generate the report document, we made an HWP 2002 document template with marker strings that were supposed to be searched and replaced with the corresponding information such as patient information and diagnosis results. The proposed system ...

• Type: Journal
• Year: 2006
• Where: JIPS
• Authors: Munho Ryu, Jong Dae Kim, Jongwon Kim
• Keywords: Automatic Reading, Diagnostic Dna Chip, DNA Chip, JIPS 2006