In this paper, we propose a compression scheme for animated semi-regular meshes. This scheme includes a spatio-temporal wavelet filtering to exploit the coherence both in time and space. In order to optimize the quantization of both spatial and temporal wavelet coefficients, the proposed compression scheme also includes a model-based bit allocation. The experimental results show that this approach significantly improves the compression performances, when comparing with previous similar approaches. Key words: Spatio-temporal decomposition, Wavelet filtering, Animation, Semi-regular meshes, Bit Allocation, Coding.