: This paper proposes CARUSO – a new SoC approach that emphasizes Connectivity, Autonomic/Organic computing principles, Real-time, and Ultra-low power requirements. The requirements shall be fulfilled by a multithreaded processor core within a reconfigurable SoC. Helper threads running with low priority in own thread slots concurrent to the application implement autonomic/organic managers that monitor the application and decide if selfconfiguration, self-healing, self-optimization, or self-protection must be triggered.