This paper presents our findings on the feasibility of doing pronoun resolution for biomedical texts, in comparison with conducting pronoun resolution for the newswire domain. In our experiments, we built a simple machine learning-based pronoun resolution system, and evaluated the system on three different corpora: MUC, ACE, and GENIA. Comparative statistics not only reveal the noticeable issues in constructing an effective pronoun resolution system for a new domain, but also provides a comprehensive view of those corpora often used for this task.