In this paper, we have proposed a framework of systems-on-chips clustering in application to complicated sensor networks. The framework can be applied to address the communication issues in distributed and large-scaled sensor nodes in wireless sensor network application. There are two communication categories under consideration, i.e. intra-nodes and inter-nodes. Due to the potentially higher frequency in the signal propagation within the sensor node, the characteristics of the interconnect among various systems-on-chips cannot be described in the traditionally lumped R, L, C components. We adapt a distributed transmission line model to address such issues and possibly improve the reliability in the intranodes communication. Furthermore, based on the bandwidth requirements of each sensor node, the large-scaled senor network is proposed to be transformed into a maze diagram by a user defined threshold bandwidth, so that many existing approaches may be applied to determine the routing pa...