Empirical studies of the variation in debt ratios across firms have used statistical models singularly to analyze the important determinants of capital structure. Researchers, however, rarely employ non-linear models to examine the determinants and make little effort to identify a superior prediction model. This study adopts multiple linear regressions and artificial neural networks (ANN) models with seven explanatory variables of corporation's feature and three external macro-economic control variables to analyze the important determinants of capital structures of the high-tech and traditional industries in Taiwan, respectively. Results of this study show that the determinants of capital structure are different in both industries. The major different determinants are business-risk and growth opportunities. Based on the values of RMSE, the ANN models achieve a better fit and forecast than the regression models for debt ratio, and ANNs are cable of catching sophisticated non-linea...