—This paper describes the application of various search techniques to the problem of automatic empirical code optimization. The search process is a critical aspect of auto-tuning systems because the large size of the search space and the cost of evaluating the candidate implementations makes it infeasible to find the true optimum point by brute force. We evaluate the effectiveness of Nelder-Mead Simplex, Genetic Algorithms, Simulated Annealing, Particle Swarm Optimization, Orthogonal search, and Random search in terms of the performance of the best candidate found under varying time limits.