The leading voice is an important feature of musical piece and can often be considered as the dominant harmonic source. We propose in this paper a new scheme for the purpose of efficient dominant harmonic source separation. This is achieved by considering a new harmonicity cue which is first compared with state-of-the-art cues using a generic evaluation methodology. The proposed separation scheme is then compared to a generic Computational Auditory Scene Analysis framework. Computational speed-up and performance comparison is done using source separation and music information retrieval tasks.