Conceptual Modeling of Genetic Studies and Pharmacogenetics

Genetic Studies examine relationships between genetic variation and disease development. Pharmacogenetics studies the responses to drugs against genetic variation. These two lines of research evaluate relationships among genotype, phenotype, and environment regarding subjects. These studies demand a variety of other information; such as clinical observations, disease development history, demographics, life style, and living environment. Correct and informative modeling of these data is critical for bioinformaticians; the model affects the capacity of data manipulation and the types of queries they can ask as well as performance of the implemented system. In this paper, we present a conceptual model on genetic studies and Pharmacogenetics using Unified Modeling Language (UML). Our model provides a comprehensive view of integrated data for genetic studies and Pharmacogenetics by incorporating genomics, experimental data, domain knowledge, research approaches, and interface data for other...

• Type: Conference
• Year: 2005
• Where: ICCSA
• Authors: Xiaohua Zhou, Il-Yeol Song
• Keywords: Applied Computing, Genetic Studies, Genetic Variation, ICCSA 2005, Studies Examine Relationships