Considerations in Making Microarray Cross-Platform Correlations

Comparison and integration of expression data derived from diverse microarray platforms is challenging. Factors affecting cross-platform comparison of microarray data include the choice of normalization method used, annotation differences, presence of splice variants, RNA degradation and probe distance from 3’ end. A thorough evaluation of two commercial microarray platforms to determine an appropriate methodology for making cross-platform correlations is described here.

• Type: Conference
• Year: 2005
• Where: CSB
• Authors: Manohar Kollegal, Sudeshna Adak, Richard Shippy, Timothy Sendera
• Keywords: Bioinformatics, Commercial Microarray Platforms, CSB 2005, Diverse Microarray Platforms, Microarray Platforms