A Data-Adaptive Approach to cDNA Microarray Image Enhancement

Abstract. A data-adaptive approach for cDNA microarray image enhancement is presented. Through the weighting coefficients adaptively determined from local microarray image statistics, the proposed technique tunes the overall filter’s detail-preserving and noise-attenuating characteristics and uses both the spatial and spectral correlation of the cDNA image during processing. Noise removal is performed by tuning a membership function which utilizes the aggregated absolute differences between the cDNA microarray inputs localized within a processing window sliding over the image.

• Type: Conference
• Year: 2005
• Where: ICCS
• Authors: Rastislav Lukac, Konstantinos N. Plataniotis, Bogdan Smolka, Anastasios N. Venetsanopoulos
• Keywords: CDNA Microarray, CDNA Microarray Image, ICCS 2005, Microarray Image Statistics