—Wide field of view (FOV) and high-resolution image acquisition is highly desirable in many vision-based applications. Several systems have reported the use of reflections off mirror pyramids to capture high-resolution, single-viewpoint, and wide-FOV images. Using a dual mirror pyramid (DMP) panoramic camera as an example, in this paper, we examine how the pyramid geometry, and the selection and placement of imager clusters can be optimized to maximize the overall panoramic FOV, sensor utilization efficiency, and image uniformity. The analysis can be generalized and applied to other pyramid-based designs.