Decentralized diagnosis of discrete event systems has received a lot of attention to deal with distributed systems or with systems that may be too large to be diagnosed by one centralized site. This paper casts the problem of decentralized diagnosis in a new hierarchical framework. A key feature is the exploitation of different local decisions together with appropriate rules for their fusion. This includes local diagnosis decisions that can be interpreted as “conditional decisions”. Under this new framework, a series of new decentralized architectures are defined and studied. The properties of their corresponding notions of decentralized diagnosability are characterized and their relationship with existing work described. Corresponding verification algorithms are also presented and on-line diagnosis strategies discussed.