DNA Library Screening, Pooling Design and Unitary Spaces

Abstract. Pooling design is an important research topic in bioinformatics due to its wide applications in molecular biology, especially DNA library screening. In this paper, with unitary spaces over finite fields, we present two new constructions whose efficiency ratio, i.e., the ratio between the number of tests and the number of items, is smaller than some of existing construction.

• Type: Conference
• Year: 2009
• Where: COCOA
• Authors: Suogang Gao, Zengti Li, Jiangchen Yu, Xiaofeng Gao, Weili Wu
• Keywords: COCOA 2009, Important Research Topic, Pooling Design, Unitary Spaces