DNA Sequence Design Using Templates

Sequence design is a crucial problem in information-based biotechnology such as DNA-based computation. We introduce a simple strategy named template method that systematically generates a set of sequences of length l such that any of its member will have approximately l/3 mismatches with other sequences, their complements, and the overlaps of their concatenations.

• Type: Journal
• Year: 2002
• Where: NGC
• Authors: Masanori Arita, Satoshi Kobayashi
• Keywords: Communications, Crucial Problem, Information-based Biotechnology, NGC 2002, Sequence Design