Dynamic Imaging and Tracer Kinetic Modeling for Emission Tomography Using Rotating Detectors

— When performing dynamic studies using emission tomography the tracer distribution changes during acquisition of a single set of projections. This is particularly true for some positron emission tomography (PET) systems which, like single photon emission computed tomography (SPECT), acquire data over a limited angle at any time, with full projections obtained by rotation of the detectors. In this paper, an approach is proposed for processing data from these systems, applicable to either PET or SPECT. A method of interpolation, based on overlapped parabolas, is used to obtain an estimate of the total counts in each pixel of the projections for each required frame-interval, which is the total time to acquire a single complete set of projections necessary for reconstruction. The resultant projections are reconstructed using traditional filtered backprojection (FBP) and tracer kinetic parameters are estimated using a method which relies on counts integrated over the frame-interval rath...

• Type: Journal
• Year: 1998
• Where: TMI
• Authors: Chi-Hoi Lau, David Dagan Feng, Brian F. Hutton, Daniel Pak-Kong Lun, Wan-Chi Siu
• Keywords: Detector, Emission Tomography, Positron Emission Tomography, TMI 1998