The investigation and the development of self-organizing systems are especially needed for operation and control in massively distributed systems such as Sensor and Actor Networks (SANETs). The main issues addressed by self-organization techniques are scalability, network lifetime, and realtime support. In the literature, biological principles are often cited as inspirations for technical solutions, especially in the domain of self-organization. This concept already resulted in a good number of solutions with significant impact such as ant-based routing and immune system inspired network security solutions. In this paper, another specific biological field is investigated: cellular signaling cascades for event-specific reaction initiated by individual cells in collaboration with their direct neighbors. Information between cells are transmitted via proteins and result in the cascade of protein