This paper proposes an efficient region-based background subtraction technique using static camera for motion detection in various monitoring applications. Color histograms, texture information, and successive division of candidate rectangular image regions are utilized to model the background and detect the motion. The proposed method combines this principle and the Gaussian mixture background modeling to produce a new method which outperforms the classic Gaussian mixture background subtraction method. It has the advantages of filtering noise during image differentiation and providing a selectable level of detail for the contour of the moving shapes. Results show that our proposed method combined with Gaussian mixture outperforms results obtained with Gaussian mixture alone, particularly in the combination with MDPA distance.