ERP Correlates of Word Production before and after Stroke in an Aphasic Patient

■ Changes in brain activity characterizing impaired speech production after brain damage have usually been investigated by comparing aphasic speakers with healthy subjects because prestroke data are normally not available. However, when interpreting the results of studies of stroke patients versus healthy controls, there is an inherent difficulty in disentangling the contribution of neuropathology from other sources of between-subject variability. In the present work, we had an unusual opportunity to study an aphasic patient with severe anomia who had incidentally performed a picture naming task in an ERP study as a control subject one year before suffering a left hemisphere stroke. The fortuitous recording of this patientʼs brain activity before his stroke allows direct comparison of his pre- and poststroke brain activity in the same language production task. The subject did not differ from other healthy subjects before his stroke, but presented major electrophysiological differen...

• Type: Journal
• Year: 2011
• Where: JOCN
• Authors: Marina Laganaro, Stéphanie Morand, Christoph M. Michel, Laurent Spinelli, Armin Schnider
• Keywords: Brain Activity, Healthy Controls, JOCN 2011, Stroke