Extracting Biochemical Reaction Kinetics from Time Series Data

We consider the problem of inferring kinetic mechanisms for biochemical reactions from time series data. Using a priori knowledge about the structure of chemical reaction kinetics we develop global nonlinear models which use elementary reactions as a basis set, and discuss model construction using top-down and bottom-up approaches.

• Type: Conference
• Year: 2004
• Where: KES
• Authors: Edmund J. Crampin, Patrick E. McSharry, Santiago Schnell
• Keywords: Biochemical Reactions, Chemical Reaction Kinetics, Global Nonlinear Models, KES 2004