This paper presents an on-going investigation on interruptions in the office caused by face-to-face interactions between knowledge workers. The study aims to identify opportunities for interactive solutions that will support both, the interrupters and the interrupted. The study involves contextual interviews and observations of how administrative assistants manage interruptions. Keywords Interruptions, Ambient Intelligence, Smart Office, Contextual study ACM Classification Keywords D.4.7 Organization and Design: Interactive systems; H.4.1 Office Automation: Groupware; H.5.2 User Interfaces: User-centered design; K.4.3 Organizational Impacts: Computer-supported collaborative work