GPFrontend and GPGraphics: graphical analysis tools for genetic association studies

Background: Most software packages for whole genome association studies are non-graphical, purely text based programs originally designed to run with UNIX-like operating systems. Graphical output is often not intended or supposed to be performed with other command line tools, e.g. gnuplot. Results: Using the Microsoft .NET 2.0 platform and Visual Studio 2005, we have created a graphical software package to analyze data from microarray whole genome association studies, both for a DNA-pooling based approach as well as regular single sample data. Part of this package was made to integrate with GenePool 0.8.2, a previously existing software suite for GNU/Linux systems, which we have modified to run in a Microsoft Windows environment. Further modifications cause it to generate some additional data. This enables GenePool to interact with the .NET parts created by us. The programs we developed are GPFrontend, a graphical user interface and frontend to use GenePool and create metadata files f...

• Type: Journal
• Year: 2010
• Where: BMCBI
• Authors: Steffen Uebe, Francesca Pasutto, Mandy Krumbiegel, Denny Schanze, Arif B. Ekici, André Reis
• Keywords: BMCBI 2010, Genome Association Studies, Most Software Packages, Software Package