Identification of the isotherm function in chromatography using CMA-ES

This paper deals with the identification of the flux for a system of conservation laws in the specific example of analytic chromatography. The fundamental equations of chromatographic process are highly non linear. The state-of-theart Evolution Strategy, CMA-ES (the Covariance Matrix Adaptation Evolution Strategy), is used to identify the parameters of the so-called isotherm function. The approach was validated on different configurations of simulated data using either one, two or three components mixtures. CMA-ES is then applied to real data cases and its results are compared to those of a gradient-based strategy.

• Type: Conference
• Year: 2007
• Where: CEC
• Authors: Mohamed Jebalia, Anne Auger, Marc Schoenauer, F. James, M. Postel
• Keywords: Adaptation Evolution Strategy, Artificial Intelligence, CEC 2007, Evolution Strategy, State-of-theart Evolution Strategy