Incorporation of a Left Ventricle Finite Element Model Defining Infarction Into the XCAT Imaging Phantom

—The 4D extended Cardiac-Torso (XCAT) phantom was developed to provide a realistic and flexible model of the human anatomy and cardiac and respiratory motions for use in medical imaging research. A prior limitation to the phantom was that it did not accurately simulate altered functions of the heart that result from cardiac pathologies such as coronary artery disease (CAD). We overcame this limitation in a previous study by combining the phantom with a finite-element (FE) mechanical model of the left ventricle (LV) capable of more realistically simulating regional defects caused by ischemia. In the present work, we extend this model giving it the ability to accurately simulate motion abnormalities caused by myocardial infarction (MI), a far more complex situation in terms of altered mechanics compared with the modeling of acute ischemia. The FE model geometry is based on high resolution CT images of a normal male subject. An anterior region was defined as infarcted and the material p...

• Type: Journal
• Year: 2011
• Where: TMI
• Authors: Alexander I. Veress, William Paul Segars, Benjamin M. W. Tsui, Grant T. Gullberg
• Keywords: FE Model, FE Model Geometry, Infarction, TMI 2011