Inter-Operator Variability in Perfusion Assessment of Tumors in MRI Using Automated AIF Detection

A method is presented for the calculation of perfusion parameters in dynamic contrast enhanced MRI. This method requires identification of enhancement curves for both tumor tissue and plasma. Inter-operator variability in the derived rate constant between plasma and extra-cellular extra-vascular space is assessed in both canine and human subjects using semi-automated tumor margin identification with both manual and automated arterial input function (AIF) identification. Experimental results show a median coefficient of variability (CV)

• Type: Conference
• Year: 2005
• Where: MICCAI
• Authors: Edward A. Ashton, Teresa McShane, Jeffrey Evelhoch
• Keywords: Contrast Enhanced Mri, Medical Imaging, Method Requires Identification, MICCAI 2005, Tumor Margin Identification