Interactive Cell Segmentation Based on Active and Semi-Supervised Learning

Automatic cell segmentation can hardly be flawless due to the complexity of image data particularly when time-lapse experiments last for a long time without biomarkers. To address this issue, we propose an interactive cell segmentation method by classifying feature-homogeneous superpixels into specific classes, which is guided by human interventions. Specifically, we propose to actively select the most informative superpixels by minimizing the expected prediction error which is upper bounded by the transductive Rademacher complexity, and then query for human annotations. After propagating the user-specified labels to the remaining unlabeled superpixels via an affinity graph, the error-prone superpixels are selected automatically and request for human verification on them; once erroneous segmentation is detected and subsequently corrected, the information is propagated efficiently over a gradually-augmented graph to un-labeled superpixels such that the analogous errors are fixe...

• Type: Journal
• Year: 2016
• Where: TMI
• Authors: Hang Su, Zhaozheng Yin, Seungil Huh, Takeo Kanade, Jun Zhu
• Keywords: Knowledge Management, TMI 2016