The throughput of wireless networks can be significantly improved by multi-channel communications compared with single-channel communications since the use of multiple channels can reduce interference influence. In this paper, we study interference-aware topology control and QoS routing in IEEE 802.11-based multi-channel wireless mesh networks with dynamic traffic. Channel assignment and routing are two basic issues in such networks. Different channel assignments can lead to different network topologies. We present a novel definition of co-channel interference. Based on this concept, we formally define and present an effective heuristic for the minimum INterference Survivable Topology Control (INSTC) problem which seeks a channel assignment for the given network such that the induced network topology is interference-minimum among all K-connected topologies. We then formulate the Bandwidth-Aware Routing (BAR) problem for a given network topology, which seeks routes for QoS connection r...