This paper describes an approach to the detection of events in complex, multi-channel, high frequency data. The example used is that of detecting the re-siting of a transcutaneous O2/CO2 probe on a baby in a neonatal intensive care unit (ICU) from the available monitor data. A software workbench has been developed which enables the expert clinician to display the data and to mark up features of interest. This knowledge is then used to define the parameters for a pattern matcher which runs over a set of intervals derived from the raw data by a new iterative interval merging algorithm. The approach has been tested on a set of 45 probe changes; the preliminary results are encouraging, with an accuracy of identification of 89%