In this article, a new fragile, blind, high payload capacity, ROI (Region of Interest) preserving Medical image watermarking (MIW) technique in the spatial domain for grayscale medical images is proposed. We present a watermarking scheme that combines lossless data compression and encryption technique in application to medical images. The effectiveness of the proposed scheme, proven through experiments on various medical images through various image quality measure matrices such as PSNR, MSE and MSSIM enables us to argue that, the method will help to maintain Electronic Patient Report (EPR)/DICOM data privacy and medical image integrity. Keywords-Image Watermarking; Electronic Patient Report; Fragile watermarking, Region of Interest.