MAVL/StickWRLD: analyzing structural constraints using interpositional dependencies in biomolecular sequence alignments

The increasing availability of structurally aligned protein families has made it possible to use statistical methods to discover regions of interpositional dependenciesof residue identity. Such dependencies amongst residues often have structural or functional implications, and their discovery can supply valuable constraints that assist in the refinement of measured, or predicted molecular structure assignments. Multiple Alignment Variation Linker (MAVL) and StickWRLD [W. Ray (2004) Nucleic Acids Res., 32, W59

• Type: Journal
• Year: 2006
• Where: NAR
• Authors: Hatice Gulcin Ozer, William C. Ray
• Keywords: Dependenciesof Residue Identity, NAR 2006, Nucleic Acid, Nucleic Acids Res