This paper addresses the design and development of MediaPick [1], an interactive multi-touch system for semantic search of multimedia contents. Our solution provides an intuitive, easy-touse way to select concepts organized according to an ontological structure and retrieve the related contents. Users are then able to examine and organize such results through semantic or subjective criteria. As use case we considered professionals who work with huge multimedia archives (journalists, archivists, editors etc.). Categories and Subject Descriptors D.2.10 [Design]: Methodologies and Representation. D.2.11 e Architecture]: Data abstraction and Domain-specific architecture. H.5.2 [User Interfaces]: Evaluation/methodology, Graphical user interfaces (GUI), Input devices and strategies, Interaction styles, Prototyping, User-centered design. H.3.3 [Information Storage and Retrieval]: Information Search and Retrieval - Search process. H.3.5 [Information Storage and Retrieval]: Online Information ...