Model-based identification of PEEP titrations during different volemic levels

A cardiovascular system (CVS) model has previously been validated in simulated cardiac and circulatory disease states. It has also been shown to accurately capture all main hemodynamic trends in a porcine model of pulmonary embolism. In this research, a slightly extended CVS model and parameter identification process are presented and validated in a porcine experiment of positive end-expiratory pressure (PEEP) titrations at different volemic levels. The model is extended to more physiologically represent the separation of venous and arterial circulation. Errors for the identified model are within 5% 1 

• Type: Journal
• Year: 2008
• Where: CMPB
• Authors: Christina Starfinger, J. Geoffrey Chase, Christopher E. Hann, Geoffrey M. Shaw, P. Lambert, Bram W. Smith, E. Sloth, A. Larsson, Steen Andreassen, Stephen E. Rees
• Keywords: CMPB 2008, Extended Cvs Model, Model, Porcine Model