A Model for Simulation of Infant Cardiovascular Response to Orthostatic Stress

We developed an infant circulation model which incorporates an accurate myocardial cell model including a beta adrenergic system. The beta adrenergic system is essential for the response reproduction of the baroreflex control system. The proposed model was constructed by modifying the parameters of a human adult circulation model with the aid of a guinea pig myocardial cell model, whose baseline heart rate is close to that of an infant. The presented model is in good agreement with results obtained in physiological experiments.

• Type: Conference
• Year: 2007
• Where: FIMH
• Authors: Yutaka Nobuaki, Akira Amano, Takao Shimayoshi, Jianyin Lu, Eun B. Shim, Tetsuya Matsuda
• Keywords: Circulation Model, FIMH 2007, Infant Circulation Model, Myocardial Cell Model