We introduce the s-Plex Editing problem generalizing the well-studied Cluster Editing problem, both being NP-hard and both being motivated by graph-based data clustering. Instead of transforming a given graph by a minimum number of edge modifications into a disjoint union of cliques (Cluster Editing), the task in the case of s-Plex Editing is now to transform a graph into a disjoint union of so-called s-plexes. Herein, an s-plex denotes a vertex set inducing a (sub)graph where every vertex has edges to all but at most s vertices in the splex. Cliques are 1-plexes. The advantage of s-plexes for s ≥ 2 is that they allow to model a more relaxed cluster notion (s-plexes instead of cliques), which better reflects inaccuracies of the input data. We develop a provably efficient and effective preprocessing based on data reduction (yielding a so-called problem kernel), a forbidden subgraph characterization of s-plex cluster graphs, and a depth-bounded search tree which is used to find opt...