Abstract. Open systems are becoming increasingly important in a variety of distributed, networked computer applications. Their characteristics, such as agent diversity, heterogeneity and fluctuation, confront multiagent learning with new challenges. This paper presents the interaction learning meta-architecture InFFrA as one possible answer to these challenges, and introduces the opponent classification heuristic ADHOC as a concrete multiagent learning method that has been designed on the basis of InFFrA. Extensive experimental validation proves the adequacy of ADHOC in a scenario of iterated multiagent games and underlines the usefulness of schemas such as InFFrA specifically tailored for open multiagent learning environments. At the same time, limitations in the performance of ADHOC suggest further improvements to the methods used here. Also, the results obtained from this study allow more general conclusions regarding the problems of learning in open systems to be drawn.