—In this paper, we propose a new interference alignment (IA) scheme designing jointly the linear transmitter and receiver for the MIMO interference channel system, using minimum total mean square error criterion, subject to individual transmit power constraints. We show that transmitter and receiver under such criterion could be realized through a joint iterative algorithm. The convergence of the proposed algorithm is discussed. We also proposed a robust MMSE-based iterative design with imperfect channel state information (CSI). The proposed robust MMSEbased iterative interference alignment scheme is shown to be less sensitive to channel estimation errors. Simulation results show that the proposed schemes outperform the existing IA schemes with fast convergence. Keywords-MIMO interference channel; interference alignment; joint transceiver; iterative algorithm; robust.