Odor stimulus inference based on neural spike signal in rats

This paper presents a novel method for inferring the odor based on neural activities observed from rats’ main olfactory bulbs. Multi-channel extra-cellular single unit recordings were done by micro-wire electrodes (tungsten, 50μm, 32 channels) implanted in the mitral/tufted cell layers of the main olfactory bulb of anesthetized rats to obtain neural responses to various odors. Neural response as a key feature was measured by substraction of neural firing rate before stimulus from after. For odor inference, we have developed a decoding method based on the maximum likelihood (ML) estimation. The results have shown that the average decoding accuracy is about 100.0%, 96.0%, 84.0%, and 100.0% with four rats, respectively. This work has profound implications for a novel brain-machine interface system for odor inference.

• Type: Journal
• Year: 2011
• Where: ICASSP
• Authors: Kyung-Jin You, Hyun Joo Lee, Yiran Lang, Changkyun Im, Chin Su Koh, Hyung-Cheul Shin, Hyun-Chool Shin
• Keywords: ICASSP 2011, Main Olfactory Bulb, Neural Response, ODOR, Signal Processing