Ontological informatics infrastructure for pharmaceutical product development and manufacturing

Informatics infrastructure plays a crucial role in supporting different decision making activities related to pharmaceutical product development, pilot plant and commercial scale manufacturing by streamlining information gathering, data integration, model development and managing all these for easy and timely access and reuse. The foundation of such an infrastructure is the explicitly and formally modeled information. This foundation enables knowledge in different forms, and best manufacturing practices, to be modeled and captured into tools to support the product lifecycle management. This paper discusses the development of ontologies, Semantic Web infrastructure and Web related technologies that make such an infrastructure development possible. While many of the issues addressed in this paper are applicable to a wide spectrum of molecular-based products, we focus our work on the development of pharmaceutical informatics to support Active Pharmaceutical Ingredient (API) as well as dr...

• Type: Journal
• Year: 2006
• Where: CCE
• Authors: Venkat Venkatasubramanian, Chunhua Zhao, Girish Joglekar, Ankur Jain, Leaelaf Hailemariam, Pradeep Suresh, Pavankumar Akkisetty, Ken Morris, Gintaras V. Reklaitis
• Keywords: CCE 2006, CCE 2007, Decision Making Activities, Pharmaceutical Product Development, Product Development