Ultra-wideband (UWB) transmission is an emerging wireless technology for future short-range indoor and outdoor multimedia applications. To coordinate the access to the wireless medium among the competing devices, the IEEE 802.15.3 medium access control (MAC) is proposed for short-range high-speed wireless personal area networks (WPANs) in the IEEE 802.15.3a task group. In the MAC, three acknowledgment (ACK) mechanisms are adopted during channel time allocation for error control over the error-prone wireless channel: No-ACK, Immediate-ACK (Imm-ACK), and Delayed-ACK (Dly-ACK). Frames received with errors can be retransmitted in the Imm-ACK and Dly-ACK mechanisms. However, how to optimally use these ACK mechanisms during channel time allocation is still an open issue. In this paper, we investigate how to configure the ACK mechanism parameters in order to achieve optimal throughput performance. We first formulate the throughput optimization problem for a contention-free channel time alloca...