Outage probabilities in wireless networks depend on various factors: the node distribution, the MAC scheme, and the models for path loss, fading and transmission success. In prior work on outage characterization for networks with randomly placed nodes, most of the emphasis was put on networks whose nodes are Poisson distributed and where ALOHA is used as the MAC protocol. In this paper we provide a general framework for the analysis of outage probabilities in the high-reliability regime. The outage probability characterization is based on two parameters: the intrinsic spatial contention of the network, introduced in [1], and the coordination level achieved by the MAC as measured by the interference scaling exponent introduced in this paper. We study outage probabilities under the signal-tointerference ratio (SIR) model, Rayleigh fading, and power-law path loss, and explain how the two parameters depend on the network model. The main result is that the outage probability approaches as...