Patient Classification of fMRI Activation Maps

The analysis of brain activations using functional magnetic resonance imaging (fMRI) is an active area of neuropsychological research. Standard techniques for analysis have traditionally focused on finding the most significant areas of brain activation, and have only recently begun to explore the importance of their spatial characteristics. We compare fMRI contrast images and significance maps to training sets of similar maps using the spatial distribution of activation values. We demonstrate that a Fisher linear discriminant (FLD) classifier for either type of map can differentiate patients from controls accurately for Alzheimer's disease, schizophrenia, and mild traumatic brain injury (MTBI).

• Type: Conference
• Year: 2003
• Where: MICCAI
• Authors: James Ford, Hany Farid, Fillia Makedon, Laura A. Flashman, Thomas W. McAllister, Vasileios Megalooikonomou, Andrew J. Saykin
• Keywords: Brain Activation, FMRI Contrast Images, Medical Imaging, MICCAI 2003, Mild Traumatic Brain