— The paper gives a summary of 2014 year results in the topic of physiological modeling and control achieved by the Physiological Controls Group of the Obuda University. The presentation is integrated in the tradition established years ago at IEEE INES conferences and 2014’s IEEE SACI conference summarizing the latest results obtained by the group. Four topics are presented, highlighting collaboration with our partner research institutes as well: modern robust control of diabetes, antiangiogenic model-based tumor control, biostatistical modeling methods of diabetes, control of peristaltic pumps in hemodialyisis problem.