Pseudogene.org: a comprehensive database and comparison platform for pseudogene annotation

The Pseudogene.org database serves as a comprehensive repository for pseudogene sequence annotation. The definition of a pseudogene varies within the literature, resulting in significantly different approaches to the problem of identification. Consequently, it is difficult to maintain a consistent collection of pseudogenes in the detail necessary for their effective use. Our database is designed to address this issue. It integrates a variety of heterogeneous resources and supports a subset structure that highlights specific groups of pseudogenes that are of interest to the research community. Tools are provided for the comparison of sets and the creation of layered set unions, enabling researchers to derive a current “consensus” set of pseudogenes. Additional features include versatile search, the capacity for robust interaction with other databases, the ability to reconstruct older versions of the database (taking into account changing genome builds), and an underlying object-ori...

• Type: Journal
• Year: 2007
• Where: NAR
• Authors: John E. Karro, Yangpan Yan, Deyou Zheng, Zhaolei Zhang, Nicholas Carriero, Philip Cayting, Paul M. Harrison, Mark Gerstein
• Keywords: Database, NAR 2007, Pseudogene Sequence Annotation, Pseudogenes