Qualitative Simulation of Genetic Regulatory Networks: Method and Application

Computer modeling and simulation are indispensable for understanding the functioning of an organism on a molecular level. We present an implemented method for the qualitative simulation of large and complex genetic regulatory networks. The method allows a broad range of regulatory interactions between genes to be represented and has been applied to the analysis of a real network of biological interest, the network controlling the inititation of sporulation in the bacterium B. subtilis.

• Type: Conference
• Year: 2001
• Where: IJCAI
• Authors: Hidde de Jong, Michel Page, Céline Hernandez, Johannes Geiselmann
• Keywords: Genetic Regulatory Networks, IJCAI 2001, IJCAI 2007, Implemented Method, Qualitative Simulation